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EXTH-74. IMPAIRED PARP1 DNA REPAIR DEFINES CHEMO-SENSITIVITY IN IDH1 MUTANT CELL
INTRODUCTION: Mutations in isocitrate dehydrogenase (IDH1/2) are the most prevalent genetic abnormalities in lower grade gliomas. The presence of IDH mutations in glioma is prognostic for better clinical outcomes with longer patient survival, and greater sensitivity to chemotherapy. In the present s...
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| Publié dans: | Neuro Oncol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692291/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.365 |
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