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EXTH-32. REPEAT ADENOSINE RECEPTOR ACTIVATION IMPROVES GBM SURVIVAL IN MICE BY TRANSIENTLY MODULATING THE BLOOD-BRAIN BARRIER
BACKGROUND: Glioblastoma (GBM) has a poor prognosis partly due to inadequate chemotherapy delivery across the blood-brain barrier (BBB). Previous studies using an adenosine A(2A) receptor (A(2A)R) agonist, regadenoson, impacted tight/adherens junctions and multi-drug resistance (MDR) proteins after...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692259/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.324 |
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