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EXTH-82. HIGH NOTCH1 EXPRESSION AND WILD-TYPE P53 DEFINE SYNERGISTIC ACTIVITY BY GAMMA SECRETASE INHIBITORS AND DOXORUBICIN IN GLIOBLASTOMAS
Glioblastoma (GBM) remains one of the most lethal and difficult-to-treat cancers. The poor prognosis of GBM patients is due in part to its resistance to available treatments, which calls for development of novel therapeutic agents/regimen. In this study, we tested a series of patient-derived primary...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692204/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.372 |
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