Glucagon receptor activates extracellular signal-regulated protein kinase 1/2 via cAMP-dependent protein kinase

We prepared a stable cell line expressing the glucagon receptor to characterize the effect of G(s)-coupled receptor stimulation on extracellular signal-regulated protein kinase 1/2 (ERK1/2) activity. Glucagon treatment of the cell line caused a dose-dependent increase in cAMP concentration, activati...

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Detalhes bibliográficos
Main Authors: Jiang, Youwei, Cypess, Aaron M., Muse, Evan D., Wu, Cui-Rong, Unson, Cecilia G., Merrifield, R. B., Sakmar, Thomas P.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC56922/
https://ncbi.nlm.nih.gov/pubmed/11517300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.131200398
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