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Expression and significance of B7-H3 and Tie-2 in the tumor vasculature of clear cell renal carcinoma
Tumor angiogenesis is required for tumor growth and metastasis, and the Ang/Tie-2 axis plays a pivotal role in angiogenesis. B7-H3, a new member of the B7 family of costimulatory molecules, has a critical function in the T-cell-mediated antitumor immune response, and abnormal tumor B7-H3 expression...
Gespeichert in:
| Veröffentlicht in: | Onco Targets Ther |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Dove Medical Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692197/ https://ncbi.nlm.nih.gov/pubmed/29180874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S147041 |
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