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Expression and significance of B7-H3 and Tie-2 in the tumor vasculature of clear cell renal carcinoma

Tumor angiogenesis is required for tumor growth and metastasis, and the Ang/Tie-2 axis plays a pivotal role in angiogenesis. B7-H3, a new member of the B7 family of costimulatory molecules, has a critical function in the T-cell-mediated antitumor immune response, and abnormal tumor B7-H3 expression...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Zhang, Xianyun, Ji, Jindong, Zhang, Guangbo, Fang, Chuntao, Jiang, Fujin, Ma, Song, Hou, Jianquan
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692197/
https://ncbi.nlm.nih.gov/pubmed/29180874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S147041
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