TMOD-49. ANTITUMOR EFFICACY OF ANTI-PDL1 IN ACTH-SECRETING PITUITARY ADENOMAS: AN IMMUNOTHERAPEUTIC APPROACH FOR CUSHING’S DISEASE

BACKGROUND: Cushing’s disease (CD) is caused by an ACTH-secreting pituitary adenoma that causes severe patient morbidity. First-line treatment for CD is surgical adenomectomy, but 25% of these patients will recur within 5-years. Targeting immune checkpoint Program Death Ligand-1 (PDL1) has emerged a...

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Veröffentlicht in:Neuro Oncol
Hauptverfasser: Elsamadicy, Aladine A, Farber, S Harrison, Chongsathidkiet, Pakawat, Kemeny, Hanna, Woroniecka, Karolina, Cui, Xiuyu, Dunn, Ian, Fecci, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692082/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1085
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