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GENE-49. ABERRANT SUPER-ENHANCERS ASSOCIATED WITH DOWNREGULATION OF RET FINGER PROTEIN OVERCOMES CHEMORESISTANCE IN GLIOBLASTOMA
RET finger protein (RFP, aka TRIM27) plays pivotal roles in acquirement of chemoresistance, via the formation of the complex with nuclear transcription factor Y (NF-Y) and histone deacetylase1 (HDAC1), which are associated with deacetylation of histone H3K27 and specific enhancer activity. Although...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Neuro Oncol |
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| Κύριοι συγγραφείς: | , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Oxford University Press
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692066/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.421 |
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