GENE-49. ABERRANT SUPER-ENHANCERS ASSOCIATED WITH DOWNREGULATION OF RET FINGER PROTEIN OVERCOMES CHEMORESISTANCE IN GLIOBLASTOMA

RET finger protein (RFP, aka TRIM27) plays pivotal roles in acquirement of chemoresistance, via the formation of the complex with nuclear transcription factor Y (NF-Y) and histone deacetylase1 (HDAC1), which are associated with deacetylation of histone H3K27 and specific enhancer activity. Although...

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Publicado no:Neuro Oncol
Main Authors: Hirano, Masaki, Ranjit, Melissa, Yamamichi, Akane, Aoki, Kosuke, Ohka, Fumiharu, Kato, Takuya, Enomoto, Atsushi, Takahashi, Masahide, Wakabayashi, Toshihiko, Natsume, Atsushi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692066/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.421
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