GENE-49. ABERRANT SUPER-ENHANCERS ASSOCIATED WITH DOWNREGULATION OF RET FINGER PROTEIN OVERCOMES CHEMORESISTANCE IN GLIOBLASTOMA

RET finger protein (RFP, aka TRIM27) plays pivotal roles in acquirement of chemoresistance, via the formation of the complex with nuclear transcription factor Y (NF-Y) and histone deacetylase1 (HDAC1), which are associated with deacetylation of histone H3K27 and specific enhancer activity. Although...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Hirano, Masaki, Ranjit, Melissa, Yamamichi, Akane, Aoki, Kosuke, Ohka, Fumiharu, Kato, Takuya, Enomoto, Atsushi, Takahashi, Masahide, Wakabayashi, Toshihiko, Natsume, Atsushi
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692066/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.421
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