SCDT-24. SYNERGISTIC EFFECTS OF VALPROIC ACID AND TRAIL-SECRETING hMSCs IN GLIOMA THERAPY

OBJECTIVE: Histone deacetylase inhibitors have been shown to enhance the sensitivity of tumor cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced cytotoxicity. Valproic acid (VPA), a histone deacetylase inhibitor (HDACi), is approved for the treatment of epilepsia, bipol...

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I publikationen:Neuro Oncol
Huvudupphovsmän: Kim, Jung-hoon, Kim, Young Joo, Jeun, Sin-soo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2017
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Abstracts
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692031/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1107
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