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SCDT-24. SYNERGISTIC EFFECTS OF VALPROIC ACID AND TRAIL-SECRETING hMSCs IN GLIOMA THERAPY
OBJECTIVE: Histone deacetylase inhibitors have been shown to enhance the sensitivity of tumor cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced cytotoxicity. Valproic acid (VPA), a histone deacetylase inhibitor (HDACi), is approved for the treatment of epilepsia, bipol...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692031/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1107 |
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