DRES-08. A NOVEL XENOGRAFT MODEL REVEALS A GENE CASCADE AND SERUM BIOMARKER DEFINING A MESENCHYMAL TRANSITION DURING THE EVOLUTION OF GLIOBLASTOMA RESISTANCE TO ANTI-ANGIOGENIC THERAPY

INTRODUCTION: Bevacizumab treatment of glioblastoma is limited by transient response and acquired resistance. To study transcriptional changes underlying the evolution of bevacizumab resistance and identify resistance biomarkers, we created a novel multigenerational xenograft model of acquired bevac...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Jahangiri, Arman, Chen, William, Nguyen, Alan, Rick, Jonathan, Kuang, Ruby, Sidorov, Maxim, Flanigan, Patrick M, Wagner, Jeffrey R, Carbonell, W Shawn, Yagnik, Garima, Aghi, Manish K
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Abstracts
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691977/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.266
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker