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DRES-01. ZEB1-MEDIATED INVASIVE MESENCHYMAL TRANSITION AT THE SINGLE CELL LEVEL PROMOTES ANTI-ANGIOGENIC THERAPY RESISTANCE IN GLIOBLASTOMA

INTRODUCTION: Bevacizumab responsiveness in glioblastoma is transient. The time course and upstream regulators of resistance still remain undefined. There is also conflicting evidence as to whether the resistance is driven by upregulated VEGF-independent angiogenic pathways or adaptation to treatmen...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Chandra, Ankush, Jahangiri, Arman, Chen, William, Yagnik, Garima, Garcia, Joseph, Nguyen, Alan, Weiss, Jacob, Wolf, Kayla, Lin, Jung-Ming, Mueller, Soeren, Rick, Jonathan, Diaz, Aaron, Gilbert, Luke, Kumar, Sanjay, Aghi, Manish
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216367/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.308
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