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CMET-12. TUMOR CELL DETECTION BY IMMUNOFLOW CYTOMETRY AND BRAF MUTATION ANALYSIS IN CEREBROSPINAL FLUID OF MELANOMA PATIENTS WITH SUSPECTED LEPTOMENINGEAL METASTASES

INTRODUCTION: Approximately five percent of melanoma patients develop leptomeningeal metastases (LM). Diagnosis of LM can be made on clinical symptoms and typical contrast enhancement of the leptomeninges on MRI brain or spine and/or CSF cytology. However, MRI has a sensitivity of 76% and a specific...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: van Bussel, Mark, Pluim, Dick, Milojkovic-Kerklaan, Bojana, van den Broek, Daan, Beijnen, Jos, Boogerd, Willem, Schellens, Jan, Rhun, Emilie Le, Brandsma, Dieta
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691889/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.161
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