CMET-12. TUMOR CELL DETECTION BY IMMUNOFLOW CYTOMETRY AND BRAF MUTATION ANALYSIS IN CEREBROSPINAL FLUID OF MELANOMA PATIENTS WITH SUSPECTED LEPTOMENINGEAL METASTASES

INTRODUCTION: Approximately five percent of melanoma patients develop leptomeningeal metastases (LM). Diagnosis of LM can be made on clinical symptoms and typical contrast enhancement of the leptomeninges on MRI brain or spine and/or CSF cytology. However, MRI has a sensitivity of 76% and a specific...

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Vydáno v:Neuro Oncol
Hlavní autoři: van Bussel, Mark, Pluim, Dick, Milojkovic-Kerklaan, Bojana, van den Broek, Daan, Beijnen, Jos, Boogerd, Willem, Schellens, Jan, Rhun, Emilie Le, Brandsma, Dieta
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691889/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.161
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