Silibinin Restores NAD(+) Levels and Induces the SIRT1/AMPK Pathway in Non-Alcoholic Fatty Liver

Nicotinamide adenine dinucleotide (NAD(+)) homeostasis is emerging as a key player in the pathogenesis of non-alcoholic fatty liver disease (NAFLD) and is tightly linked to the SIRT1/5’-AMP-activated protein kinase (AMPK) pathway. Silibinin, the main component of silymarin, has been proposed as a nu...

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Detalhes bibliográficos
Publicado no:Nutrients
Main Authors: Salomone, Federico, Barbagallo, Ignazio, Godos, Justyna, Lembo, Vincenzo, Currenti, Walter, Cinà, Diana, Avola, Roberto, D’Orazio, Nicolantonio, Morisco, Filomena, Galvano, Fabio, Li Volti, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691703/
https://ncbi.nlm.nih.gov/pubmed/28973994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu9101086
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