Effect of silibinin on endothelial dysfunction and ADMA levels in obese diabetic mice

BACKGROUND: Cardiovascular diseases (CVD) in diabetic patients have endothelial dysfunction as a key pathogenetic event. Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase (NOS), plays a pivotal role in endothelial dysfunction. Different natural polyphenols have bee...

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Detalles Bibliográficos
Main Authors: Li Volti, Giovanni, Salomone, Salvatore, Sorrenti, Valeria, Mangiameli, Andrea, Urso, Vincenzo, Siarkos, Ilias, Galvano, Fabio, Salamone, Federico
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
Assuntos:
Original Investigation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152512/
https://ncbi.nlm.nih.gov/pubmed/21756303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-10-62
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