Protein Inhibitor of Activated STAT2 Restricts HCV Replication by Modulating Viral Proteins Degradation

Hepatitis C virus (HCV) replication in cells is controlled by many host factors. In this report, we found that protein inhibitor of activated STAT2 (PIAS2), which is a small ubiquitin-like modifier (SUMO) E3 ligase, restricted HCV replication. During infection, HCV core, NS3 and NS5A protein express...

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Bibliografske podrobnosti
izdano v:Viruses
Main Authors: Guo, Jing, Chen, Dan, Gao, Xiaoxiao, Hu, Xue, Zhou, Yuan, Wu, Chunchen, Wang, Yun, Chen, Jizheng, Pei, Rongjuan, Chen, Xinwen
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691636/
https://ncbi.nlm.nih.gov/pubmed/28973998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v9100285
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