PLA1A Participates in the Antiviral Innate Immune Response by Facilitating the Recruitment of TANK-Binding Kinase 1 to Mitochondria

As a key molecule in the antiviral innate immune response, the activation of TANK-binding kinase 1 (TBK1) is under tight regulation. In this report, we identified phosphatidylserine-specific phospholipase PLA1A as a host factor that modulates the TBK1 activation. Knockdown of PLA1A expression suppre...

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Detalhes bibliográficos
Publicado no:J Innate Immun
Main Authors: Gao, Xiaoxiao, Chen, Dan, Hu, Xue, Zhou, Yuan, Wang, Yun, Wu, Chunchen, Chen, Jizheng, Wang, Yanyi, Pei, Rongjuan, Chen, Xinwen
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757148/
https://ncbi.nlm.nih.gov/pubmed/30016790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000489832
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