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Depletion of FoxP3(+) Tregs improves control of larval Echinococcus multilocularis infection by promoting co‐stimulation and Th1/17 immunity

INTRODUCTION: The growth potential of the tumor‐like Echinococcus multilocularis metacestode (causing alveolar echinococcosis, AE) is directly linked to the nature/function of the periparasitic host immune‐mediated processes. Previous studies had shown that regulatory T cells (Tregs) become graduall...

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Библиографические подробности
Опубликовано в: :Immun Inflamm Dis
Главные авторы: Wang, Junhua, Müller, Stephan, Lin, Renyong, Siffert, Myriam, Vuitton, Dominique A., Wen, Hao, Gottstein, Bruno
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691311/
https://ncbi.nlm.nih.gov/pubmed/28621034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.181
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