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Sinonasal T-cell expression of cytotoxic mediators granzyme B and perforin is reduced in patients with chronic rhinosinusitis
BACKGROUND: CD8(+) T cells and natural killer (NK) cells are cytotoxic cells that use granzyme B (GrB) and perforin. Defective cytotoxic function is known to play a role in dysregulated immune response as seen in chronic sinusitis, also referred to as chronic rhinosinusitis (CRS). However, to our kn...
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| Pubblicato in: | Am J Rhinol Allergy |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
OceanSide Publications, Inc.
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5691237/ https://ncbi.nlm.nih.gov/pubmed/29122079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2500/ajra.2017.31.4474 |
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