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Developmental excitatory-to-inhibitory GABA-polarity switch is disrupted in 22q11.2 deletion syndrome: a potential target for clinical therapeutics

Individuals with 22q11.2 microdeletion syndrome (22q11.2 DS) show cognitive and behavioral dysfunctions, developmental delays in childhood and risk of developing schizophrenia and autism. Despite extensive previous studies in adult animal models, a possible embryonic root of this syndrome has not be...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Amin, Hayder, Marinaro, Federica, De Pietri Tonelli, Davide, Berdondini, Luca
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691208/
https://ncbi.nlm.nih.gov/pubmed/29146941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15793-9
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