Enforced GFI1 expression impedes human and murine leukemic cell growth

The differentiation of haematopoietic cells is regulated by a plethora of so-called transcription factors (TFs). Mutations in genes encoding TFs or graded reduction in their expression levels can induce the development of various malignant diseases such as acute myeloid leukaemia (AML). Growth Facto...

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Udgivet i:Sci Rep
Main Authors: Hönes, Judith M., Thivakaran, Aniththa, Botezatu, Lacramioara, Patnana, Pradeep, Castro, Symone Vitoriano da Conceição, Al-Matary, Yahya S., Schütte, Judith, Fischer, Karen B. I., Vassen, Lothar, Görgens, André, Dührsen, Ulrich, Giebel, Bernd, Khandanpour, Cyrus
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691148/
https://ncbi.nlm.nih.gov/pubmed/29147018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15866-9
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