Novel Bis-Cyclic Guanidines as Potent Membrane-Active Antibacterial Agents with Therapeutic Potential

We designed a class of small dimeric cyclic guanidine derivatives, which display potent antibacterial activity against both multidrug-resistant Gram-negative and Gram-positive bacteria. They could compromise bacterial membranes without developing resistance, inhibit biofilms formed by E. Coli, and e...

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Detaylı Bibliyografya
Yayımlandı:Chem Commun (Camb)
Asıl Yazarlar: Teng, Peng, Nimmagadda, Alekhya, Su, Ma, Hong, Yuzhu, Shen, Ning, Li, Chunpu, Tsai, Ling-Yu, Cao, Jessica, Li, Qi, Cai, Jianfeng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5690803/
https://ncbi.nlm.nih.gov/pubmed/29052670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc07285f
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