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Novel Bis-Cyclic Guanidines as Potent Membrane-Active Antibacterial Agents with Therapeutic Potential
We designed a class of small dimeric cyclic guanidine derivatives, which display potent antibacterial activity against both multidrug-resistant Gram-negative and Gram-positive bacteria. They could compromise bacterial membranes without developing resistance, inhibit biofilms formed by E. Coli, and e...
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| 出版年: | Chem Commun (Camb) |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5690803/ https://ncbi.nlm.nih.gov/pubmed/29052670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc07285f |
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