Stochastic loss and gain of symmetric divisions in the C. elegans epidermis perturbs robustness of stem cell number

Biological systems are subject to inherent stochasticity. Nevertheless, development is remarkably robust, ensuring the consistency of key phenotypic traits such as correct cell numbers in a certain tissue. It is currently unclear which genes modulate phenotypic variability, what their relationship i...

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Xehetasun bibliografikoak
Argitaratua izan da:PLoS Biol
Egile Nagusiak: Katsanos, Dimitris, Koneru, Sneha L., Mestek Boukhibar, Lamia, Gritti, Nicola, Ghose, Ritobrata, Appleford, Peter J., Doitsidou, Maria, Woollard, Alison, van Zon, Jeroen S., Poole, Richard J., Barkoulas, Michalis
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2017
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5690688/
https://ncbi.nlm.nih.gov/pubmed/29108019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2002429
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