Downregulation of KCNMB4 expression and changes in BK channel subtype in hippocampal granule neurons following seizure activity

A major challenge is to understand maladaptive changes in ion channels that sets neurons on a course towards epilepsy development. Voltage- and calcium-activated K+ (BK) channels contribute to early spike timing in neurons, and studies indicate that the BK channel plays a pathological role in increa...

Full description

Saved in:
Bibliographic Details
Published in:PLoS One
Main Authors: Whitmire, Luke E., Ling, Ling, Bugay, Vladslav, Carver, Chase M., Timilsina, Santosh, Chuang, Hui-Hsiu, Jaffe, David B., Shapiro, Mark S., Cavazos, Jose E., Brenner, Robert
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5690595/
https://ncbi.nlm.nih.gov/pubmed/29145442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188064
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items