Protein tyrosine phosphatase 1B deficiency in podocytes mitigates hyperglycemia-induced renal injury

OBJECTIVE: Diabetic nephropathy is one of the most devastating complications of diabetes, and growing evidence implicates podocyte dysfunction in disease pathogenesis. The objective of this study was to investigate the contribution of protein tyrosine phosphatase 1B (PTP1B) in podocytes to hyperglyc...

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Detalhes bibliográficos
Publicado no:Metabolism
Main Authors: Ito, Yoshihiro, Hsu, Ming-Fo, Bettaieb, Ahmed, Koike, Shinichiro, Mello, Aline, Calvo-Rubio, Miguel, Villalba, Jose M., Haj, Fawaz G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5690491/
https://ncbi.nlm.nih.gov/pubmed/28987240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2017.07.009
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