Human Neural Stem Cell Biodistribution and Predicted Tumor Coverage by a Diffusible Therapeutic in a Mouse Glioma Model

Engineered neural stem cells (NSCs) intrinsically migrating to brain tumors offer a promising mechanism for local therapeutic delivery. However, difficulties in quantitative assessments of NSC migration and in estimates of tumor coverage by diffusible therapeutics have impeded development and refine...

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Vydáno v:Stem Cells Transl Med
Hlavní autoři: Barish, Michael E., Herrmann, Kelsey, Tang, Yang, Argalian Herculian, Siranush, Metz, Marianne, Aramburo, Soraya, Tirughana, Revathiswari, Gutova, Margarita, Annala, Alexander, Moats, Rex A., Goldstein, Leanne, Rockne, Russell C., Gutierrez, Jennifer, Brown, Christine E., Ghoda, Lucy, Aboody, Karen S.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
Translational Research Articles and Reviews
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5689763/
https://ncbi.nlm.nih.gov/pubmed/28481046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.16-0397
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