Kaempferol induces autophagic cell death of hepatocellular carcinoma cells via activating AMPK signaling

In the present study, we demonstrate that Kaempferol inhibited survival and proliferation of established human hepatocellular carcinoma (HCC) cell lines (HepG2, Huh-7, BEL7402, and SMMC) and primary human HCC cells. Kaempferol treatment in HCC cells induced profound AMP-activated protein kinase (AMP...

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Vydáno v:Oncotarget
Hlavní autoři: Han, Bing, Yu, Yi-Qun, Yang, Qi-Lian, Shen, Chun-Ying, Wang, Xiao-Juan
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5689680/
https://ncbi.nlm.nih.gov/pubmed/29156790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21043
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