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Post-surgery fluids promote transition of cancer stem cell-to-endothelial and AKT/mTOR activity, contributing to relapse of giant cell tumors of bone

Giant cell tumors of bone (GCTB) are rare sarcomas with a high rate of unpredictable local relapse. Studies suggest that surgical methods affect recurrence, supporting the idea that local disease develops from re-growth of residual cancer cells. To identify early prognostic markers of individual ris...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Fazioli, Flavio, Colella, Gianluca, Miceli, Roberta, Di Salvatore, Mariano Giuseppe, Gallo, Michele, Boccella, Serena, De Chiara, Annarosaria, Ruosi, Carlo, de Nigris, Filomena
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5689592/
https://ncbi.nlm.nih.gov/pubmed/29156702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18783
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