A prenatal interruption of DISC1 function in the brain exhibits a lasting impact on adult behaviors, brain metabolism, and interneuron development

Mental illnesses like schizophrenia (SCZ) and major depression disorder (MDD) are devastating brain disorders. The SCZ risk gene, disrupted in schizophrenia 1 (DISC1), has been associated with neuropsychiatric conditions. However, little is known regarding the long-lasting impacts on brain metabolis...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Deng, Dazhi, Jian, Chongdong, Lei, Ling, Zhou, Yijing, McSweeney, Colleen, Dong, Fengping, Shen, Yilun, Zou, Donghua, Wang, Yonggang, Wu, Yuan, Zhang, Limin, Mao, Yingwei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper:Pathology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5689574/
https://ncbi.nlm.nih.gov/pubmed/29156684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21381
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