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Deletion of CTNNB1 in inhibitory circuitry contributes to autism-associated behavioral defects
Mutations in β-catenin (CTNNB1) have been implicated in cancer and mental disorders. Recently, loss-of-function mutations of CTNNB1 were linked to intellectual disability (ID), and rare mutations were identified in patients with autism spectrum disorder (ASD). As a key regulator of the canonical Wnt...
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| Publicado no: | Hum Mol Genet |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5181638/ https://ncbi.nlm.nih.gov/pubmed/27131348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw131 |
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