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Manganese superoxide dismutase and glutathione peroxidase-1 contribute to the rise and fall of mitochondrial reactive oxygen species which drive oncogenesis()

Reactive oxygen species (ROS) largely originating in the mitochondria play essential roles in the metabolic and (epi)genetic reprogramming of cancer cell evolution towards more aggressive phenotypes. Recent studies have indicated that the activity of superoxide dismutase (SOD2) may promote tumor pro...

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Publicat a:Biochim Biophys Acta
Autors principals: Ekoue, Dede N., He, Chenxia, Diamond, Alan M., Bonini, Marcelo G.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5689482/
https://ncbi.nlm.nih.gov/pubmed/28087256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2017.01.006
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