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TGF-β2 initiates autophagy via Smad and non-Smad pathway to promote glioma cells’ invasion

BACKGROUND: Glioblastoma multiforme (GBM) is characterized by lethal aggressiveness and patients with GBM are in urgent need for new therapeutic avenues to improve quality of life. Current studies on tumor invasion focused on roles of cytokines in tumor microenvironment and numerous evidence suggest...

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Bibliografiske detaljer
Udgivet i:J Exp Clin Cancer Res
Main Authors: Zhang, Chao, Zhang, Xin, Xu, Ran, Huang, Bin, Chen, An-Jing, Li, Chao, Wang, Jian, Li, Xin-Gang
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5689187/
https://ncbi.nlm.nih.gov/pubmed/29145888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0628-8
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