MicroRNA-183-5p Increases with Age in Bone-Derived Extracellular Vesicles, Suppresses Bone Marrow Stromal (Stem) Cell Proliferation, and Induces Stem Cell Senescence

Microvesicle- and exosome-mediated transport of microRNAs (miRNAs) represents a novel cellular and molecular pathway for cell–cell communication. In this study, we tested the hypothesis that these extracellular vesicles (EVs) and their miRNAs might change with age, contributing to age-related stem c...

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Publicat a:Tissue Eng Part A
Autors principals: Davis, Colleen, Dukes, Amy, Drewry, Michelle, Helwa, Inas, Johnson, Maribeth H., Isales, Carlos M., Hill, William D., Liu, Yutao, Shi, Xingming, Fulzele, Sadanand, Hamrick, Mark W.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2017
Matèries:
Special Focus Articles*
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5689127/
https://ncbi.nlm.nih.gov/pubmed/28363268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2016.0525
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