MiR‐335 overexpression impairs insulin secretion through defective priming of insulin vesicles

MicroRNAs contribute to the maintenance of optimal cellular functions by fine‐tuning protein expression levels. In the pancreatic β‐cells, imbalances in the exocytotic machinery components lead to impaired insulin secretion and type 2 diabetes (T2D). We hypothesize that dysregulated miRNA expression...

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Dades bibliogràfiques
Publicat a:Physiol Rep
Autors principals: Salunkhe, Vishal A., Ofori, Jones K., Gandasi, Nikhil R., Salö, Sofia A., Hansson, Sofia, Andersson, Markus E., Wendt, Anna, Barg, Sebastian, Esguerra, Jonathan L. S., Eliasson, Lena
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688784/
https://ncbi.nlm.nih.gov/pubmed/29122960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13493
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