MiR‐335 overexpression impairs insulin secretion through defective priming of insulin vesicles

MicroRNAs contribute to the maintenance of optimal cellular functions by fine‐tuning protein expression levels. In the pancreatic β‐cells, imbalances in the exocytotic machinery components lead to impaired insulin secretion and type 2 diabetes (T2D). We hypothesize that dysregulated miRNA expression...

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Dettagli Bibliografici
Pubblicato in:Physiol Rep
Autori principali: Salunkhe, Vishal A., Ofori, Jones K., Gandasi, Nikhil R., Salö, Sofia A., Hansson, Sofia, Andersson, Markus E., Wendt, Anna, Barg, Sebastian, Esguerra, Jonathan L. S., Eliasson, Lena
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688784/
https://ncbi.nlm.nih.gov/pubmed/29122960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13493
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