MiR‐335 overexpression impairs insulin secretion through defective priming of insulin vesicles

MicroRNAs contribute to the maintenance of optimal cellular functions by fine‐tuning protein expression levels. In the pancreatic β‐cells, imbalances in the exocytotic machinery components lead to impaired insulin secretion and type 2 diabetes (T2D). We hypothesize that dysregulated miRNA expression...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Physiol Rep
Egile Nagusiak: Salunkhe, Vishal A., Ofori, Jones K., Gandasi, Nikhil R., Salö, Sofia A., Hansson, Sofia, Andersson, Markus E., Wendt, Anna, Barg, Sebastian, Esguerra, Jonathan L. S., Eliasson, Lena
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2017
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688784/
https://ncbi.nlm.nih.gov/pubmed/29122960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13493
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