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FOXP1 Promotes Embryonic Neural Stem Cell Differentiation by Repressing Jagged1 Expression

Mutations in FOXP1 have been linked to neurodevelopmental disorders including intellectual disability and autism; however, the underlying molecular mechanisms remain ill-defined. Here, we demonstrate with RNA and chromatin immunoprecipitation sequencing that FOXP1 directly regulates genes controllin...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Braccioli, Luca, Vervoort, Stephin J., Adolfs, Youri, Heijnen, Cobi J., Basak, Onur, Pasterkamp, R. Jeroen, Nijboer, Cora H., Coffer, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688236/
https://ncbi.nlm.nih.gov/pubmed/29141232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.10.012
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