An open-label study to assess the feasibility and tolerability of rilmenidine for the treatment of Huntington’s disease

Preclinical data have shown that rilmenidine can regulate autophagy in models of Huntington’s disease (HD), providing a potential route to alter the disease course in patients. Consequently, a 2-year open-label study examining the tolerability and feasibility of rilmenidine in mild-moderate HD was u...

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Vydáno v:J Neurol
Hlavní autoři: Underwood, Benjamin R., Green-Thompson, Zeyn W., Pugh, Peter J., Lazic, Stanley E., Mason, Sarah L., Griffin, Jules, Jones, P. Simon, Rowe, James B., Rubinsztein, David C., Barker, Roger A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2017
Témata:
Original Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688221/
https://ncbi.nlm.nih.gov/pubmed/29075837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00415-017-8647-0
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