The PRDM9 KRAB domain is required for meiosis and involved in protein interactions

PR domain-containing protein 9 (PRDM9) is a major regulator of the localization of meiotic recombination hotspots in the human and mouse genomes. This role involves its DNA-binding domain, which is composed of a tandem array of zinc fingers, and PRDM9-dependent trimethylation of histone H3 at lysine...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Chromosoma
Prif Awduron: Imai, Yukiko, Baudat, Frédéric, Taillepierre, Miguel, Stanzione, Marcello, Toth, Attila, de Massy, Bernard
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer Berlin Heidelberg 2017
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688218/
https://ncbi.nlm.nih.gov/pubmed/28527011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-017-0631-z
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