The psoriasis-associated IL-17A induces and cooperates with IL-36 cytokines to control keratinocyte differentiation and function

Psoriasis is a T(H)17-driven inflammatory disease affecting a significant proportion of the world population. The molecular consequences of IL-17 signaling in the skin are only partially understood. Therefore, we evaluated the IL-17A effects on organotypic 3-dimensional skin models and observed that...

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Vydáno v:Sci Rep
Hlavní autoři: Pfaff, Carolina M., Marquardt, Yvonne, Fietkau, Katharina, Baron, Jens M., Lüscher, Bernhard
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688102/
https://ncbi.nlm.nih.gov/pubmed/29142248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15892-7
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