Quantitative Modeling of the Dynamics and Intracellular Trafficking of Far-Red Light-Activatable Prodrugs: Implications in Stimuli-Responsive Drug Delivery System

The combination of photodynamic therapy (PDT) with anti-tumor agents is a complimentary strategy to treat local cancers. We developed a unique photosensitizer (PS)-conjugated paclitaxel (PTX) prodrug in which a PS is excited by near-infrared wavelength light to site-specifically release PTX while ge...

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Pubblicato in:J Pharmacokinet Pharmacodyn
Autori principali: Li, Mengjie, Thapa, Pritam, Rajaputra, Pallavi, Bio, Moses, Peer, Cody J., Figg, William D., You, Youngjae, Woo, Sukyung
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688019/
https://ncbi.nlm.nih.gov/pubmed/28913666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-017-9543-z
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