A Latent Propriospinal Network Can Restore Diaphragm Function After High Cervical Spinal Cord Injury

Spinal cord injury (SCI) above cervical level 4 disrupts descending axons from the medulla that innervate phrenic motor neurons, causing permanent paralysis of the diaphragm. Using an ex vivo preparation in neonatal mice, we have identified an excitatory spinal network which can direct phrenic motor...

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Bibliographic Details
Published in:Cell Rep
Main Authors: Cregg, Jared M., Chu, Kevin A., Hager, Lydia E., Maggard, Rachel S. J., Stoltz, Daimen R., Edmond, Michaela, Alilain, Warren J., Philippidou, Polyxeni, Landmesser, Lynn T., Silver, Jerry
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5687843/
https://ncbi.nlm.nih.gov/pubmed/29045834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.09.076
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