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Topoisomerase IIβ Selectively Regulates Motor Neuron Identity and Peripheral Connectivity through Hox/Pbx-Dependent Transcriptional Programs

Vital motor functions, such as respiration and locomotion, rely on the ability of spinal motor neurons (MNs) to acquire stereotypical positions in the ventral spinal cord and to project with high precision to their peripheral targets. These key properties of MNs emerge during development through tra...

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Publicat a:eNeuro
Autors principals: Edmond, Michaela, Hanley, Olivia, Philippidou, Polyxeni
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5779120/
https://ncbi.nlm.nih.gov/pubmed/29379870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0404-17.2017
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