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Infectious Entry and Neutralization of Pathogenic JC Polyomaviruses

Progressive multifocal leukoencephalopathy (PML) is a lethal brain disease caused by uncontrolled replication of JC polyomavirus (JCV). JCV strains recovered from the brains of PML patients carry mutations that prevent the engagement of sialylated glycans, which are thought to serve as receptors for...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Geoghegan, Eileen M., Pastrana, Diana V., Schowalter, Rachel M., Ray, Upasana, Gao, Wei, Ho, Mitchell, Pauly, Gary T., Sigano, Dina M., Kaynor, Campbell, Cahir-McFarland, Ellen, Combaluzier, Benoit, Grimm, Jan, Buck, Christopher B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5687836/
https://ncbi.nlm.nih.gov/pubmed/29091757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.10.027
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