Broadly neutralizing human monoclonal JC polyomavirus VP1–specific antibodies as candidate therapeutics for progressive multifocal leukoencephalopathy

In immunocompromised individuals, JC polyomavirus (JCPyV) may mutate and gain access to the central nervous system resulting in progressive multifocal leukoencephalopathy (PML), an often fatal opportunistic infection for which no treatments are currently available. Despite recent progress, the contr...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Jelcic, Ivan, Combaluzier, Benoit, Jelcic, Ilijas, Faigle, Wolfgang, Senn, Luzia, Reinhart, Brenda J., Ströh, Luisa, Nitsch, Roger M., Stehle, Thilo, Sospedra, Mireia, Grimm, Jan, Martin, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820754/
https://ncbi.nlm.nih.gov/pubmed/26400911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aac8691
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