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Broadly neutralizing human monoclonal JC polyomavirus VP1–specific antibodies as candidate therapeutics for progressive multifocal leukoencephalopathy

In immunocompromised individuals, JC polyomavirus (JCPyV) may mutate and gain access to the central nervous system resulting in progressive multifocal leukoencephalopathy (PML), an often fatal opportunistic infection for which no treatments are currently available. Despite recent progress, the contr...

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Bibliografiske detaljer
Udgivet i:Sci Transl Med
Main Authors: Jelcic, Ivan, Combaluzier, Benoit, Jelcic, Ilijas, Faigle, Wolfgang, Senn, Luzia, Reinhart, Brenda J., Ströh, Luisa, Nitsch, Roger M., Stehle, Thilo, Sospedra, Mireia, Grimm, Jan, Martin, Roland
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820754/
https://ncbi.nlm.nih.gov/pubmed/26400911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aac8691
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