Pediatric Non-Down Syndrome Acute Megakaryoblastic Leukemia is Characterized by Distinct Genomic Subsets with Varying Outcomes

Acute Megakaryoblastic Leukemia (AMKL) is a subtype of acute myeloid leukemia (AML) in which cells morphologically resemble abnormal megakaryoblasts. While rare in adults, AMKL accounts for 4–15% of newly diagnosed childhood AML(1–3). AMKL in patients without Down syndrome (non-DS-AMKL) is frequentl...

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Detaylı Bibliyografya
Yayımlandı:Nat Genet
Asıl Yazarlar: de Rooij, Jasmijn D.E., Branstetter, Cristyn, Ma, Jing, Li, Yongjin, Walsh, Michael P., Cheng, Jinjun, Obulkasim, Askar, Dang, Jinjun, Easton, John, Verboon, Lonneke J., Mulder, Heather L., Zimmermann, Martin, Koss, Cary, Gupta, Pankaj, Edmonson, Michael, Rusch, Michael, Lim, Joshua Yew Suang, Reinhardt, Katarina, Pigazzi, Martina, Song, Guangchun, Yeoh, Allen Eng Juh, Shih, Lee-Yung, Liang, Der-Cherng, Halene, Stephanie, Krause, Diane S., Zhang, Jinghui, Downing, James R., Locatelli, Franco, Reinhardt, Dirk, van den Heuvel-Eibrink, Marry M., Zwaan, C. Michel, Fornerod, Maarten, Gruber, Tanja A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5687824/
https://ncbi.nlm.nih.gov/pubmed/28112737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3772
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