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hYSK1 promotes cancer cell proliferation and migration through negative regulation of p16(INK4a) under hypoxic conditions

The alteration of expression of p16(INK4a), a well-known cyclin-dependent kinase inhibitor involved in cell cycle control, in tumors is unclear, especially under hypoxic conditions. To evaluate p16(INK4a) regulation, we performed a protein microarray analysis. Among 1,800 proteins in the array, we i...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lee, Mee-Hyun, Dong, Zigang, Surh, Young-Joon, Choi, Bu Young
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5687670/
https://ncbi.nlm.nih.gov/pubmed/29179500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21654
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